Addition of cyclosporine to adalimumab improved psoriasis and adalimumab-induced injection site reaction

Adalimumab induced pulmonary sarcoid reaction

Sarcoidosis is a multisystem granulomatous inflammatory disease of unknown etiology. There is evidence that Tumor Necrosis Factor alpha (TNF-α) antagonists are useful in the treatment of advanced or refractory disease. However, sarcoidosis-like reaction has been reported with TNF-α blockade in other inflammatory conditions. Here we report a case of sarcoid-like reaction in a patient with psoria...

Treating psoriasis with adalimumab

Psoriasis is a common, chronic, inflammatory skin disease that can have a significant impact on the quality of life of those who are afflicted. Recent advances in the understanding of the pathophysiology of psoriasis have led to the development of new, genetically engineered, targeted therapies for this disease. Among the most successful strategies for treatment has been the use of biologic imm...

Injection site reaction to adalimumab: Positive skin test and successful rapid desensitisation.

ibuprofen was positive in a residual lesion, while patch test with the same drug was negative in upper back. We were curious to know if our patient was sensitised to the rest of the propionic acid group, but due to the small area affected skin, we could not test these additional drugs. Therefore all propionic acid group drugs were forbidden. The patient tolerated acetylsalicylic acid, and then ...

Visual Loss Induced by Adalimumab Used for Plaque Psoriasis

A 61-year-old Caucasian male with severe plaque psoriasis without joint involvement was initiated on adalimumab therapy. Shortly thereafter he presented to the emergency room with acute loss of vision in the right eye. A comprehensive systemic workup was instituted which included magnetic resonance imaging (MRI) with and without gadolinium of the brain and orbits. MRI revealed findings that wer...

[Adalimumab-induced urticaria].